OVERACTIVE AUTOPHAGY IS A PATHOLOGICAL MECHANISM UNDERLYING PREMATURE SUTURE OSSIFICATION IN NONSYNDROMIC CRANIOSYNOSTOSIS

Overactive autophagy is a pathological mechanism underlying premature suture ossification in nonsyndromic craniosynostosis

Abstract Nonsyndromic craniosynostosis (NSC) is the most common craniosynostosis with the primary defect being one or more fused sutures.In contrast to syndromic craniosynostosis, the etiopathogenesis of NSC is largely unknown.Here we show that autophagy, a major catabolic process required for the maintenance of bone homeostasis and bone growth, is

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Biostimulation as a Means for Optimizing Fruit Phytochemical Content and Functional Quality of Tomato Landraces of the San Marzano Area

The effect of plant biostimulation on fruits of ACTIVE GREEN TEA traditional tomato germplasm is largely unknown.We examined how a tropical plant-derived biostimulant impacts the nutritional, functional, and compositional characteristics of tomato fruits from four landraces, collected in the San Marzano (SM) tomato Protected Designation of Origin (

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MACRONUTRIENT CONCENTRATION AND CONTENT IN PASSION FRUIT LEAVES UNDER SAMPLING METHODS AND N-K FERTILIZATION RATES

ABSTRACT Nitrogen and potassium fertilization and assessment of adequate nutritional status are essential for increasing fruit production of passion fruit.However, studies related to characterization Revenge of the Fallen of the leaf nutrient concentration and content in passion fruit with different production capacities are scarce in the literatur

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